更多最新信息参见我们课题组网站(随时更新):
https://www.x-mol.com/groups/Wan_Jie-Ping
研究方向:有机合成,药物合成
联系方式:wanjieping@126.com; wanjieping@jxnu.edu.cn
简介:
万结平,男,教授。博士、硕士生导师,英国皇家化学学会(RSC Chemistry) top 1%年度高被引中国学者,威廉希尔娱乐“正大学者”特聘教授。2010年6月毕业于浙江大学化学系获理学博士学位。受国家基金委中德科学基金资助,2011-2012年在德国亚琛工业大学从事合作研究。目前主要研究兴趣为多功能平台合成子(platform synthons)和实用试剂的开发应用、多样性导向合成、环境友好型催化以及相关的有机化合物生物活性研究等。独立工作以来,已经发表专业领域学术论文100余篇,论文被引用2500余次,H-index为29。作为第一完成人,获得国家发明专利授权5项。目前已经培养毕业硕士10余名,所有毕业生毕业成绩均为“双优(即论文评审和答辩成绩均为优秀)”,其中7人/次获得过研究生国家奖学金,多人获得省/校级优秀论文。个人获得主要荣誉和奖励有:英国皇家化学学会(RSC Chemistry)top 1%年度高被引中国学者,江西省自然科学三等奖(第一完成人),Thieme Chemistry Journal Award (2014)、江西省杰出青年基金、威廉希尔娱乐熊智明奖教金、威廉希尔娱乐“三育人”先进工作者、浙江省优秀毕业生、浙江大学优秀毕业生、浙江大学三好研究生、赢创奖学金(德国赢创-德固赛集团)等。主持(含已完成)国家自然科学基金2项,江西省自然科学基金青年重大项目1项,江西省自然科学基金2项,其它开放及厅局级课题多项。受邀担任Chemical Reviews, ACS Catalysis, Organic Letter, Green Chemistry, Chemical Communications, Chemistry-A European Journal, Journal of Organic Chemistry, Organic Chemistry Frontiers, Organic & Biomolecular Chemistry, New Journal of Chemistry, RSC Advances, Tetrahedron, European Journal of Organic Chemistry, Synthesis, Synlett, Current Organic Chemistry, Synthetic Communications, Mini-review in Organic Chemistry, Chinese Journal of Chemistry, ChemistryOpen, 《有机化学》,《化学通报》等多十余个国内国际化学期刊审稿人。
欢迎有志于从事有机合成研究的研究生和本科生同学加入课题组工作、学习!
主持科研项目:
国家自然科学基金地区基金 (no. 21861019)
国家自然科学基金地区基金 (no. 21562025)
国家自然科学基金青年基金 (no. 21102059,完成)
中德科学中心林岛青年学者计划 (no. GZ710,亚琛工大,完成)
江西省自然科学基金青年重大项目 (20161ACB21010,完成)
江西省杰出青年基金 (20162BCB23023,完成)
江西省自然科学基金面上项目 (20151BAB203008,完成)
江西省自然科学基金青年基金 (no. 20114BAB213005,完成)
浙江中医药大学基础医学院中药开放基金重点项目
江西省教育厅基金 (GJJ13245,完成)
威廉希尔娱乐青年英才计划项目(首批入选) (2012.01-2014.12,完成)
威廉希尔娱乐博士启动基金
工作以来发表的代表性论文 (最新及详细论文发表情况,参见课题组网站)
(30) Leiling Deng, Xiaoji Cao, Yunyun Liu,* Jie-Ping Wan.* In-Water Synthesis of 5-Thiolated 1,2,3-Triazoles from β-Thioenaminones by Diazo Transfer Reaction. Journal of Organic Chemistry 2019, in press, DOI: 10.1021/acs.joc.9b01817.
(29) Xixi Zheng, Jie-Ping Wan.* The C=C Double Bond Decomposition Initiated by Enamine‐Azide Cycloaddition for Catalyst‐ and Additive‐Free Synthesis of N‐Sulfonyl Amidines. Advanced Synthesis & Catalysis 2019, in press, DOI: 10.1002/adsc.201901054.
(28) Lu Gan, Yong Gao, Li Wei, Jie-Ping Wan.* Synthesis of α-Keto Thioamides by Metal-Free C═C Bond Cleavage in Enaminones Using Elemental Sulfur. Journal of Organic Chemistry 2019, 84, 1064-1069.
(27) Jie-Ping Wan,* Zhi Tu,# Yuyun Wang.# Transient and Recyclable Halogenation Coupling (TRHC) for Isoflavonoid Synthesis with Site‐Selective Arylation. Chemistry-A European Journal 2019, 25, 6907-6910. (# = equal contribution)
(26) Yanhui Guo, Guodong Wang, Li Wei, Jie-Ping Wan.* Domino C-H Sulfonylation and Pyrazole Annulation for Fully Substituted Pyrazole Synthesis in Water Using Hydrophilic Enaminones. Journal of Organic Chemistry 2019, 84, 2984-2990.
(25) Yong Gao, Yunyun Liu, Jie-Ping Wan. Visible Light-Induced Thiocyanation of Enaminone C–H Bond to Access Polyfunctionalized Alkenes and Thiocyano Chromones. Journal of Organic Chemistry 2019, 84, 2243-2251.
(24) Qing Yu, Yating Zhang, Jie-Ping Wan.* Ambient and aerobic carbon–carbon bond cleavage toward α-ketoester synthesis by transition-metal-free photocatalysis. Green Chemistry 2019, 21, 3436-3441.
(23) Lu Yang, Li Wei, Jie-Ping Wan.* Redox neutral [4+2] benzannulation of dienals and tertiary enaminones for benzaldehyde synthesis. Chemical Communications 2018, 54, 7475-7478.
(22) Yanhui Guo, Yunfeng Xiang, Li Wei, Jie-Ping Wan.* Thermoinduced Free-Radical C–H Acyloxylation of Tertiary Enaminones: Catalyst-Free Synthesis of Acyloxyl Chromones and Enaminones. Organic Letters 2018, 20, 3971-3974.
(21) Jiarui Sun, Xiangsheng Cheng, John Kamanda Mansaray, Weihong Fei, Jieping Wan,* Weijun Yao.* A copper-catalyzed three component reaction of aryl acetylene, sulfonyl azide and enaminone to form iminolactone via 6π electrocyclization. Chemical Communications 2018, 54, 13953-13956.
(20) Shuo Cao, Yunyun Liu, Changfeng Hu, Chengping Wen,* Jie-Ping Wan.* Alkyl Propiolates Participated [3+2] Annulation for the Switchable Synthesis of 1,5‐ and 1,4‐Disubstituted 1,2,3‐Triazoles Containing Ester Side Chain. ChemCatChem 2018, 10, 5007-5011.
(19) Yunyun Liu,* Yi Zhang, Jie-Ping Wan.* Multicomponent Synthesis of Diverse o-Arylated Benzamides via o-Aminophenol (OAP) Directed C(sp2)-H Arylation. Journal of Organic Chemistry 2017, 82, 8950-8957.
(18) Shanshan Zhong, Yunyun Liu, Xiaoji Cao, Jie-Ping Wan.* KIO3‐Catalyzed Domino C(sp2)−H Bond Sulfenylation and C−N Bond Oxygenation of Enaminones toward the Synthesis of 3‐Sulfenylated Chromones. ChemCatChem 2017, 9, 465-468.
(17) Jie-Ping Wan,* Shanshan Zhong, Lili Xie, Xiaoji Cao, Yunyun Liu, Li Wei. KIO3-Catalyzed aerobic cross-coupling reactions of enaminones and thiophenols: synthesis of polyfunctionalized alkenes by metal-free C–H sulfenylation. Organic Letters 2016, 18, 584-587.
(16) Jie-Ping Wan,* Shuo Cao, Yunyun Liu. Base-promoted synthesis of n-substituted 1,2,3-triazoles via enaminone–azide cycloaddition involving Regitz diazo transfer. Organic Letters 2016, 18, 6034-6037.
(15) Jie-Ping Wan,* Yunfang Lin, Xiaoji Cao, Yunyun Liu, Li Wei. Copper-catalyzed, hypervalent iodine mediated C=C bond activation of enaminones for the synthesis of α-keto amides. Chemical Communications 2016, 52, 1270-1273.
(14) Jie-Ping Wan,* Youyi Zhou, Yunyun Liu, Shouri Sheng.* Metal-free oxidative carbonylation on enaminone C=C bond for the cascade synthesis of benzothiazole-containing vicinal diketones. Green Chemistry 2016, 18, 402-405.
(13) Jie-Ping Wan,* Yanfeng Jing, Changfeng Hu, Shouri Sheng.* Metal-free synthesis of fully substituted pyridines via ring construction based on the domino reactions of enaminones and aldehydes. Journal of Organic Chemistry 2016, 81, 6826-6831.
(12) Jie-Ping Wan, Yi Li, Yunyun Liu.* Annulation based on 8-aminoquinoline assisted C–H activation: an emerging tool in N-heterocycle construction. Organic Chemistry Frontiers 2016, 3, 768-772.
(11) Yunyun Liu, Bin Huang, Xiaoji Cao, Jie-Ping Wan.* Tunable di- and mono-γ-C−H arylation of phenylacetamides by palladium-catalyzed domino reactions. ChemCatChem 2016, 8, 1470-1473.
(10) Jie-Ping Wan,* Yong Gao, Li Wei.* Recent Advances in Transition-Metal-Free Oxygenation of Alkene C=C Double Bonds for Carbonyl Generation. Chemistry-An Asian Journal 2016, 11, 2092-2102.
(9) Jie-Ping Wan,* Yong Gao. Domino Reactions Based on Combinatorial Bond Transformations in Electron-Deficient Tertiary Enamines. The Chemical Record 2016, 16, 1164-1177.
(8) Jie-Ping Wan,* Shuo Cao, Yunyun Liu. A Metal- and azide-free multicomponent assembly toward regioselective construction of 1,5-disubstituted 1,2,3-triazoles. Journal of Organic Chemistry 2015, 80, 9028-9033.
(7) Shuo Cao, Shanshan Zhong, Luoting Xin, Jie-Ping Wan.* Chengping Wen.* Visible-Light-Induced C=C Bond Cleavage of Enaminones for the Synthesis of 1,2-Diketones and Quinoxalines in Sustainable Medium. ChemCatChem 2015, 7, 1478-1482.
(6) Jie-Ping Wan,* Deqing Hu, Yunyun Liu, Shouri Sheng.* Azide-Free Synthesis of 1,2,3-Triazoles: New Opportunity for Sustainable Synthesis. ChemCatChem 2015, 7, 901-903.
(5) Jie-Ping Wan,* Hang Wang, Yunyun Liu, Hanfeng Ding.* Synthesis of 2-vinylbenzofurans via the copper-catalyzed multicomponent reactions involving an oxa-Michael/arylation/vinylation cascade. Organic Letters 2014, 16, 5160-5163.
(4) Jie-Ping Wan,* Yunfang Lin, Qing Huang, Yunyun Liu. Diastereoselective construction of tetrahydropyridine fused bicyclic structures via three-component domino reaction. Journal of Organic Chemistry 2014, 79, 7232-7238.
(3) Jie-Ping Wan,* Youyi Zhou, Shuo Cao. Domino reactions involving the branched C–N and C═C cleavage of enaminones toward pyridines synthesis. Journal of Organic Chemistry 2014, 79, 9872-9877.
(2) Yunyun Liu,* Hang Wang, Jie-Ping Wan.* Copper-catalyzed, C–C coupling-based one-pot tandem reactions for the synthesis of benzofurans using o-iodophenols, acyl chlorides, and phosphorus ylides. Journal of Organic Chemistry 2014, 79, 10599-10604.
(1) Jie-Ping Wan, Charles, C. J. Loh, Fangfang Pan, Dieter Enders.* Enantioselective organocatalytic domino synthesis of tetrahydropyridin-2-ols. Chemical Communications 2012, 48, 10499-10051.
英文论著
(1) Wan Jie-Ping, chapter 4: Silicon mediated multicomponent reactions, in Multicomponent reactions 2, Science of Synthesis. Ed: T. J. J. Müller, Georg Thieme Verlag KG. 2013, pp377-408.
(2) Wan Jie-Ping, chapter 5: The application of acetone and acetate, in Solvents and Reagents in Organic Synthesis-Reactions and Applications. Ed. Xiao-Feng Wu, Wiley-VCH, 2017, pp161-197.
授权发明专利
(1) 万结平,周友谊,刘云云。一种多组分反应合成具有不对称结构1.4-二氢吡啶及其衍生物的方法。ZL 201310418468.8。
(2) 万结平,周友谊,刘云云。一种合成N,N-双取代烯胺酮类化合物的新方法。ZL 201410158357.2。
(3) 万结平,刘云云,周友谊,林云芳,汪航。一种高效选择性合成β-烯氨酯和烯胺酮的方法。ZL 201210499533.X。
(4) 万结平,刘云云,张毅。一种邻碘苯甲腈的制备方法。ZL 201510237028.1。
(5) 万结平,刘云云,张毅。一种基于硫粉合成噻蒽的方法。ZL 201510176702.X。
学术会议报告
[7] 万结平。烯胺酮特征性转化应用:异黄酮和苯甲醛合成新方法,第十六届全国均相催化会议,Flashtalk,武汉,2019,9.26-9.29.
[6] 万结平。C-H Elaboration of Enaminones By Cross-Coupling Transformation. 全国第十四届有机合成化学学术研讨会,口头报告。淮北,2017,10.26-10.29。
[5] 万结平。缺电子烯胺的多样性键官能化反应,2017江南大学首届药物化学与有机合成学术论坛,邀请报告。无锡,2017,9.14-9.16。
[4] Jie-Ping Wan. Enaminone as a platform in diversity oriented synthesis. The 12th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-12). One-minute Oral presentation. Xi’an, China. 2017, 1102-1105.
[3] 万结平。基于缺电子烯胺多样性转化模式的新合成方法研究。第十三届全国有机合成化学学术研讨会,邀请报告。扬州,2016,10.13-10.15。
[2] 万结平。基于缺电子烯胺的多样性合成:C−H转化到C=C转化。第九届全国有机化学化学会议,口头报告。长春,2015,7.28-7.31。
[1] 万结平。多组分反应研究中的一些新尝试。第八届全国有机化学化学会议,邀请报告。重庆,2013. 10.17-10.20。
信息最近更新时间:2019年11月